This information is disseminated under the sponsorship of the U.S. Department of Transportation
in the interest of information exchange.
The United States Government assumes no Liability for the contents or use thereof.
Amitriptyline |
| Description |
Amitriptyline is a tricyclic antidepressant used to treat depression, attention-deficit hyperactivity disorder, and panic, phobia and eating disorders. Plasma protein binding is 95%. |
| Therapeutic Low |
0.0050 |
| Therapeutic High |
0.2000 |
| Units |
ug/mL |
| Specimen |
P |
| Half Life Low |
8.00 |
| Half Life High |
51.00 |
| VOD Low |
6.00 |
| VOD High |
10.00 |
| Toxic Level |
0.500 |
| Lethal Level |
2.000 |
| Plasma to Whole Blood ratio |
1.20 |
| Warnings |
Warnings - may impair mental and/or physical ability required for the performance of potentially hazardous tasks (e.g., driving, operating heavy machinery). |