This information is disseminated under the sponsorship of the U.S. Department of Transportation in the interest of information exchange. The United States Government assumes no Liability for the contents or use thereof.

Butalbital

Description Butalbital is a short- to intermediate-acting barbiturate. It is commonly used in combination with other drugs such as acetaminophen and caffeine to treat mild to moderate pain, migraines and tension headaches. Specimen/blood ratio: muscle (0.66 +/- 0.09), liver (2.22 +/- 0.04), liver fluid (0.89 +/- 0.23), kidney (0.98 +/- 0.09), lung (0.87 +/- 0.06), spleen (0.75 +/- 0.03), brain (0.96 +/- 0.07), bile (0.94 +/- 0.22), heart (0.91 +/- 0.17), and urine (0.73 +/- 0.16). 
Therapeutic Low 1.0000
Therapeutic High 10.0000
Units ug/mL 
Specimen
Half Life Low 30.00
Half Life High 40.00
VOD Low 0.00
VOD High 1.00
Toxic Level 7.000
Lethal Level 13.000
Plasma to Whole Blood ratio 0.00
Warnings Warnings - may impair mental and/or physical ability required for the performance of potentially hazardous tasks (e.g., driving, operating heavy machinery).