This information is disseminated under the sponsorship of the U.S. Department of Transportation
in the interest of information exchange.
The United States Government assumes no Liability for the contents or use thereof.
Fluoxetine |
| Description |
An atypical antidepressant (SSRI) with the selective serotonin reuptake inhibiting action. It is biotransformed to the active metabolite, norfluoxetine. |
| Therapeutic Low |
0.0900 |
| Therapeutic High |
0.4000 |
| Units |
ug/mL |
| Specimen |
P |
| Half Life Low |
24.00 |
| Half Life High |
72.00 |
| VOD Low |
20.00 |
| VOD High |
42.00 |
| Toxic Level |
1.000 |
| Lethal Level |
6.000 |
| Plasma to Whole Blood ratio |
0.96 |
| Warnings |
Side effects of fluoxetine include insomnia, anxiety, and headache; manic behavior and suicidal ideation have also been reported. Warnings - may impair mental and/or physical ability required for the performance of potentially hazardous tasks (e.g., driving, operating heavy machinery). |